Other possible reasons include leftover files from earlier installations, corrupted system files, or conflicts with other programs. Now that you know the causes, let’s discuss the solutions.
1. Delete the AMD Radeon Profile
The gmdb.blb file houses the AMD Radeon software profile with all configurations. If corrupted, it may stop the software from opening. Deleting the CN folder will clear this profile, allowing it to regenerate with fresh settings when the software is launched again. This process resets configurations, removing any outdated or corrupted data that might prevent the software from starting.
2. Disable Integrated GPU
An integrated GPU is built into the processor and may conflict with AMD Radeon Software if not disabled. Disable it in Device Manager to prevent interference with the dedicated AMD GPU. This ensures the system prioritizes the AMD card, allowing the software to function correctly.
3. Roll Back to the Older Version of Your Graphics Driver
New driver updates can cause compatibility issues with Radeon Software. Rolling back to an older version can resolve these conflicts. If problems started after an update, roll back or perform a clean installation of the driver and software. If rolling back doesn’t help, try reinstalling.
4. Match the Driver Version to the Registry Editor
An outdated driver version in the Registry Editor can cause issues, even with the latest driver installed. Aligning the Registry Editor’s driver version with the installed Radeon Software resolves these mismatches and reduces conflicts.
5. Clean Reinstall of GPU Drivers
If the issue persists, perform a clean reinstallation of the graphics driver using Display Driver Uninstaller (DDU) to remove drivers and registry files. This clears lingering files or corrupted data, ensuring only the most recent stable drivers are installed, eliminating compatibility issues and resolving software launch errors.
6. Use the System Restore Utility
If reinstalling the graphics driver doesn’t fix the issue, use System Restore to revert to a state where AMD Radeon Software worked. This can undo changes causing conflicts without affecting personal files. If no restore point exists, reset or reinstall Windows.
