Mostly, this issue originates server-side due to the security certificate presented by the specific server, Windows Live Mail, mismatching the URL being used for connection. In some instances, though, the problem could also stem from glitches or problems on the client’s end. Here are some of the most efficient solutions that you could implement to resolve this issue:

Solution 1: Wait out the storm

Server-side hiccups are the most common cause of this problem, and if the cause is server-side, the problem is almost certainly going to be temporary. That being the case, if you have run into this issue, your best bet would be to simply close down Windows Live Mail and check back in a few hours or so to see whether or not the problem has been resolved. If a significant amount of time goes by and the issue persists, the cause may not be server-side at all and may, in fact, be on your side.

Solution 2: Restart your computer

Many Windows users affected by this issue have found success simply by restarting their computers and subsequently syncing with their email accounts upon boot-up. So, in simple terms:

Solution 3: Remove and then reconfigure your email account

Another effective solution to resolve this issue is to remove your email account from Windows Live Mail and then reconfigure it. Certain settings and/or preferences specific to your email account could be the root cause behind this problem. There’s a reasonable chance that eliminating your email account from Windows Live Mail and re-configuring it from scratch will help to alleviate this issue.

Solution 4: Ensure that your computer’s SSL settings are correct

Solution 5: Make sure that your computer’s proxy settings are correct

Solution 6: Make sure that Internet Explorer is not set to work offline

If you have Internet Explorer set to work offline, Windows Live Mail will not be able to access the internet and, as a result, will not be able to sync with and retrieve email messages from your email account. That being the case, making sure that Internet Explorer is not set to work offline is definitely worth a shot. In order to do so, you need to:

How to Fix Windows Live Mail Can t Sync and Displays Server Error 0x80072F06 - 14How to Fix Windows Live Mail Can t Sync and Displays Server Error 0x80072F06 - 79